Country, sex, EDSS change and therapy choice independently predict treatment discontinuation in multiple sclerosis and clinically isolated syndrome.

Country, sex, EDSS change and therapy choice independently predict treatment discontinuation in multiple sclerosis and clinically isolated syndrome.

OBJECTIVES: We conducted a prospective study, MSBASIS, to assess factors leading to first treatment discontinuation in patients with a clinically isolated syndrome (CIS) and early relapsing-remitting multiple sclerosis (RRMS). METHODS: The MSBASIS Study, conducted by MSBase Study Group members, enro...

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Main Authors: Claire Meyniel, Timothy Spelman, Vilija G Jokubaitis, Maria Trojano, Guillermo Izquierdo, François Grand'Maison, Celia Oreja-Guevara, Cavit Boz, Alessandra Lugaresi, Marc Girard, Pierre Grammond, Gerardo Iuliano, Marcela Fiol, Jose Antonio Cabrera-Gomez, Ricardo Fernandez-Bolanos, Giorgio Giuliani, Jeannette Lechner-Scott, Edgardo Cristiano, Joseph Herbert, Tatjana Petkovska-Boskova, Roberto Bergamaschi, Vincent van Pesch, Fraser Moore, Norbert Vella, Mark Slee, Vetere Santiago, Michael Barnett, Eva Havrdova, Carolyn Young, Carmen-Adella Sirbu, Mary Tanner, Michelle Rutherford, Helmut Butzkueven, MSBasis Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3387159?pdf=render

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http://europepmc.org/articles/PMC3387159?pdf=render

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