Quantitative Chemical Proteomics Reveals Resveratrol Inhibition of A549 Cell Migration Through Binding Multiple Targets to Regulate Cytoskeletal Remodeling and Suppress EMT

Resveratrol (RSV), a health-promoting natural product, has been shown to affect various cellular processes in tumor cells. However, the specific protein targets of RSV and the mechanism of action (MOA) of its anticancer effect remain elusive. In this study, the pharmacological activity of RSV was fi...

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Bibliographic Details
Main Authors: Xiao Chen, Yutong Wang, Jing Tian, Yurou Shao, Bo Zhu, Jigang Wang, Zichun Hua
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Pharmacology
Subjects:
EMT
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.636213/full