Markov modelling of viral load adjusting for CD4 orthogonal variable and multivariate conditional autoregressive mapping of the HIV immunological outcomes among ART patients in Zimbabwe

Abstract Background This study aimed to jointly model HIV disease progression patterns based on viral load (VL) among adult ART patients adjusting for the time-varying “incremental transients states” variable, and the CD4 cell counts orthogonal variable in a single 5-stage time-homogenous multistate...

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Bibliographic Details
Main Authors: Zvifadzo Matsena Zingoni, Tobias F. Chirwa, Jim Todd, Eustasius Musenge
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Theoretical Biology and Medical Modelling
Subjects:
Online Access:https://doi.org/10.1186/s12976-021-00145-y