A DLG2 deficiency in mice leads to reduced sociability and increased repetitive behavior accompanied by aberrant synaptic transmission in the dorsal striatum

A DLG2 deficiency in mice leads to reduced sociability and increased repetitive behavior accompanied by aberrant synaptic transmission in the dorsal striatum

Abstract Background DLG2, also known as postsynaptic density protein-93 (PSD-93) or chapsyn-110, is an excitatory postsynaptic scaffolding protein that interacts with synaptic surface receptors and signaling molecules. A recent study has demonstrated that mutations in the DLG2 promoter region are si...

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Bibliographic Details
Main Authors: Taesun Yoo, Sun-Gyun Kim, Soo Hyun Yang, Hyun Kim, Eunjoon Kim, Soo Young Kim
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Molecular Autism
Subjects:
Autism
PSD-93
Locomotion
Social interaction
Self-grooming
Striatum
Online Access:http://link.springer.com/article/10.1186/s13229-020-00324-7

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http://link.springer.com/article/10.1186/s13229-020-00324-7

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