Venlafaxine-Induced Cytotoxicity Towards Isolated Rat Hepatocytes Involves Oxidative Stress and Mitochondrial/Lysosomal Dysfunction

Purpose: Depression is a public disorder worldwide. Despite the widespread use of venlafaxine in the treatment of depression, it has been associated with the incidence of toxicities. Hence, the goal of the current investigation was to evaluate the mechanisms of venlafaxine–induced cell death in the...

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Bibliographic Details
Main Authors: Elham Ahmadian, Hossein Babaei, Alireza Mohajjel Nayebi, Aziz Eftekhari, Mohammad Ali Eghbal
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2016-12-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Online Access:http://journals.tbzmed.ac.ir/APB/Manuscript/APB-6-521.pdf