P2x7 receptors control demyelination and inflammation in the cuprizone model

The contribution of P2x7 receptors to multiple sclerosis remains controversial, as both detrimental and beneficial effects resulting from P2x7 receptor loss-of-function have been reported in autoimmune models of the disease. Here we investigated the relevance of P2x7 receptors to de- and remyelinati...

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Bibliographic Details
Main Authors: Ana Bernal-Chico, Andrea Manterola, Raffaela Cipriani, István Katona, Carlos Matute, Susana Mato
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354620300272