Beauvericin counteracted multi-drug resistant Candida albicans by blocking ABC transporters

Beauvericin counteracted multi-drug resistant Candida albicans by blocking ABC transporters

Multi-drug resistance of pathogenic microorganisms is becoming a serious threat, particularly to immunocompromised populations. The high mortality of systematic fungal infections necessitates novel antifungal drugs and therapies. Unfortunately, with traditional drug discovery approaches, only echino...

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Bibliographic Details
Main Authors: Yaojun Tong, Mei Liu, Yu Zhang, Xueting Liu, Ren Huang, Fuhang Song, Huanqin Dai, Biao Ren, Nuo Sun, Gang Pei, Jiang Bian, Xin-Ming Jia, Guanghua Huang, Xuyu Zhou, Shaojie Li, Buchang Zhang, Takashi Fukuda, Hiroshi Tomoda, Satoshi Ōmura, Richard D. Cannon, Richard Calderone, Lixin Zhang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2016-09-01
Series:Synthetic and Systems Biotechnology
Subjects:
Candida albicans
ABC transporter
Beauvericin
Virtual screening
Multi-drug resistance
Synergy
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X16300461

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http://www.sciencedirect.com/science/article/pii/S2405805X16300461

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