NLRP3 Inflammasome as a Molecular Marker in Diabetic Cardiomyopathy

NLRP3 Inflammasome as a Molecular Marker in Diabetic Cardiomyopathy

Diabetic cardiomyopathy (DCM), a common consequence of longstanding diabetes mellitus, is initiated by death of cardiomyocyte. Hyperglycemia-induced reactive oxygen species (ROS) overproduction is a major contributor of the chronic low-grade inflammation that characterizes as the DCM. ROS may promot...

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Bibliographic Details
Main Authors: Beibei Luo, Feng Huang, Yanli Liu, Yiying Liang, Zhe Wei, Honghong Ke, Zhiyu Zeng, Weiqiang Huang, Yan He
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Physiology
Subjects:
NLRP3 inflammasome
thioredoxin interacting/inhibiting protein
pyroptosis
inflammation
diabetic cardiomyopathy
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2017.00519/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2017.00519/full

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