Inhibition of lung cancer growth and metastasis by DHA and its metabolite, RvD1, through miR-138-5p/FOXC1 pathway

Abstract Background Non small cell lung cancer (NSCLC) is one of the most common cancers in the world. DHA is known to be capable of suppressing NSCLC cell proliferation and metastasis. However, the mechanisms by which DHA exhibits its antitumor effects are unknown. Here we aimed to identify the eff...

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Bibliographic Details
Main Authors: Xiaoming Bai, Jiaofang Shao, Sujin Zhou, Zhenggang Zhao, Fanghong Li, Rong Xiang, Allan Z. Zhao, Jinshun Pan
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13046-019-1478-3