Colocalization of protein kinase A with adenylyl cyclase enhances protein kinase A activity during induction of long-lasting long-term-potentiation.

The ability of neurons to differentially respond to specific temporal and spatial input patterns underlies information storage in neural circuits. One means of achieving spatial specificity is to restrict signaling molecules to particular subcellular compartments using anchoring molecules such as A-...

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Bibliographic Details
Main Authors: Myungsook Kim, Alan Jung Park, Robbert Havekes, Andrew Chay, Leonardo Antonio Guercio, Rodrigo Freire Oliveira, Ted Abel, Kim T Blackwell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-06-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3127802?pdf=render