Different intra-cerebrospinal distribution of linezolid in patients with inflammatory meningitis

Linezolid has excellent antibiotic activity against gram-positive organisms and is expected to be an alternative to vancomycin for the treatment of bacterial meningitis. Accumulated evidence has shown the superior pharmacokinetic characteristics of linezolid to vancomycin, such as cerebrospinal flui...

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Bibliographic Details
Main Authors: Naoki Ichinose, Gakushi Yoshikawa, Eri Fukao, Mai Ichisawa, Tomoaki Takahata, Yuki Enoki, Kazuaki Taguchi, Toshimi Oda, Kazuo Tsutsumi, Kazuaki Matsumoto
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:International Journal of Infectious Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971221006317