Alteration of DNA Damage Response Causes Cleft Palate

Cleft palate is one of the most common craniofacial birth defects, however, little is known about how changes in the DNA damage response (DDR) cause cleft palate. To determine the role of DDR during palatogenesis, the DDR process was altered using a pharmacological intervention approach. A compromis...

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Bibliographic Details
Main Authors: Hiroyuki Yamaguchi, Kohei Kitami, Xiao Wu, Li He, Jianbo Wang, Bin Wang, Yoshihiro Komatsu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.649492/full