Suppression of Antifolate Resistance by Targeting the Myosin Va Trafficking Pathway in Melanoma

Human melanoma is a significant clinical problem. As most melanoma patients relapse with lethal drug-resistant disease, understanding and preventing mechanism(s) of resistance is one of the highest priorities to improve melanoma therapy. Melanosomal sequestration and the cellular exportation of cyt...

Full description

Bibliographic Details
Main Authors: María Piedad Fernández-Pérez, María F. Montenegro, Magalí Sáez-Ayala, Luis Sánchez-del-Campo, Antonio Piñero-Madrona, Juan Cabezas-Herrera, José Neptuno Rodríguez-López
Format: Article
Language:English
Published: Elsevier 2013-07-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558613800760