Grape seed proanthocyanidin extract inhibits glutamate-induced cell death through inhibition of calcium signals and nitric oxide formation in cultured rat hippocampal neurons

<p>Abstract</p> <p>Background</p> <p>Proanthocyanidin is a polyphenolic bioflavonoid with known antioxidant activity. Some flavonoids have a modulatory effect on [Ca<sup>2+</sup>]<sub>i</sub>. Although proanthocyanidin extract from blueberries re...

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Bibliographic Details
Main Authors: Kim Myung-Jun, Hong Yi, Jeong Imju, Kim Hee, Ahn Seo-Hee, Rhie Duck-Joo, Jo Yang-Hyeok, Hahn Sang, Yoon Shin
Format: Article
Language:English
Published: BMC 2011-08-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/12/78