Yap Regulates Müller Glia Reprogramming in Damaged Zebrafish Retinas

Vertebrates such as zebrafish have the outstanding ability to fully regenerate their retina upon injury, while mammals, including humans, do not. In zebrafish, upon light-induced injury, photoreceptor regeneration is achieved through reprogramming of Müller glia cells, which proliferate and give ris...

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Bibliographic Details
Main Authors: Raquel Lourenço, Ana S. Brandão, Jorge Borbinha, Rita Gorgulho, António Jacinto
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.667796/full