Induced pluripotent stem cells show metabolomic differences to embryonic stem cells in polyunsaturated phosphatidylcholines and primary metabolism.

Induced pluripotent stem cells show metabolomic differences to embryonic stem cells in polyunsaturated phosphatidylcholines and primary metabolism.

Induced pluripotent stem cells are different from embryonic stem cells as shown by epigenetic and genomics analyses. Depending on cell types and culture conditions, such genetic alterations can lead to different metabolic phenotypes which may impact replication rates, membrane properties and cell di...

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Bibliographic Details
Main Authors: John K Meissen, Benjamin T K Yuen, Tobias Kind, John W Riggs, Dinesh K Barupal, Paul S Knoepfler, Oliver Fiehn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3471894?pdf=render

Internet

http://europepmc.org/articles/PMC3471894?pdf=render

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