4mCPred-MTL: Accurate Identification of DNA 4mC Sites in Multiple Species Using Multi-Task Deep Learning Based on Multi-Head Attention Mechanism

4mCPred-MTL: Accurate Identification of DNA 4mC Sites in Multiple Species Using Multi-Task Deep Learning Based on Multi-Head Attention Mechanism

DNA methylation is one of the most extensive epigenetic modifications. DNA 4mC modification plays a key role in regulating chromatin structure and gene expression. In this study, we proposed a generic 4mC computational predictor, namely, 4mCPred-MTL using multi-task learning coupled with Transformer...

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Bibliographic Details
Main Authors: Rao Zeng, Song Cheng, Minghong Liao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
multi-task learning
feature sharing
DNA 4mC modification
epigenetics
deep learning
transformer
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.664669/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.664669/full

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