Homoharringtonine Exerts Anti-tumor Effects in Hepatocellular Carcinoma Through Activation of the Hippo Pathway

Homoharringtonine Exerts Anti-tumor Effects in Hepatocellular Carcinoma Through Activation of the Hippo Pathway

Hepatocellular carcinoma (HCC) is the most prevalent subtype of liver cancer with a mortality rate of approximately 3–6/100,000 and is the third leading cause of cancer-related death worldwide. Although several small-molecule drugs have been developed for the treatment of HCC, the choice of an agent...

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Bibliographic Details
Main Authors: Haina Wang, Rui Wang, Dan Huang, Sihan Li, Beibei Gao, Zhijie Kang, Bo Tang, Jiajun Xie, Fanzhi Yan, Rui Liang, Hua Li, Jinsong Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Pharmacology
Subjects:
homoharringtonine
hepatocellular carcinoma
apoptosis
hippo pathway
cell-cycle arrest
proliferation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.592071/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.592071/full

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