A host transcriptional signature for presymptomatic detection of infection in humans exposed to influenza H1N1 or H3N2.

There is great potential for host-based gene expression analysis to impact the early diagnosis of infectious diseases. In particular, the influenza pandemic of 2009 highlighted the challenges and limitations of traditional pathogen-based testing for suspected upper respiratory viral infection. We in...

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Bibliographic Details
Main Authors: Christopher W Woods, Micah T McClain, Minhua Chen, Aimee K Zaas, Bradly P Nicholson, Jay Varkey, Timothy Veldman, Stephen F Kingsmore, Yongsheng Huang, Robert Lambkin-Williams, Anthony G Gilbert, Alfred O Hero, Elizabeth Ramsburg, Seth Glickman, Joseph E Lucas, Lawrence Carin, Geoffrey S Ginsburg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3541408?pdf=render