Normalisation to blood activity is required for the accurate quantification of Na/I symporter ectopic expression by SPECT/CT in individual subjects.

Normalisation to blood activity is required for the accurate quantification of Na/I symporter ectopic expression by SPECT/CT in individual subjects.

The utilisation of the Na/I symporter (NIS) and associated radiotracers as a reporter system for imaging gene expression is now reaching the clinical setting in cancer gene therapy applications. However, a formal assessment of the methodology in terms of normalisation of the data still remains to be...

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Main Authors: Peggy Richard-Fiardo, Philippe R Franken, Audrey Lamit, Robert Marsault, Julien Guglielmi, Béatrice Cambien, Fanny Graslin, Sabine Lindenthal, Jacques Darcourt, Thierry Pourcher, Georges Vassaux
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22470517/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22470517/?tool=EBI

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