Methods to Detect MHC-Specific IgE in Mice and Men

Methods to Detect MHC-Specific IgE in Mice and Men

Humoral immunity is a major barrier limiting long-term outcome after organ transplantation. Especially, the production of antibodies directed against donor HLA/MHC antigens (i.e. donor-specific antibodies (DSA)) leading to antibody-mediated rejection (ABMR) is considered to be a major factor negativ...

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Bibliographic Details
Main Authors: Anna Marianne Weijler, Jasmin Mucha, Andreas Michael Farkas, Ulrike Baranyi, Nina Pilat, Ara Cho, Moritz Muckenhuber, Stefan Hopf, Markus Wahrmann, Birgit Linhart, Rudolf Valenta, Thomas Wekerle
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
transplantation
antibody-mediated rejection
donor specific antibodies
MHC
HLA
IgE
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.586856/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.586856/full

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