Novel Selective IDO1 Inhibitors with Isoxazolo[5,4-<i>d</i>]pyrimidin-4(5<i>H</i>)-one Scaffold
Indoleamine 2,3-dioxygenase 1 (IDO1) is a promising target in immunomodulation of several pathological conditions, especially cancers. Here we present the synthesis of a series of IDO1 inhibitors with the novel isoxazolo[5,4-<i>d</i>]pyrimidin-4(5<i>H</i>)-one scaffold. A foc...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-03-01
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| Series: | Pharmaceuticals |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1424-8247/14/3/265 |