The major roles of DNA polymerases epsilon and delta at the eukaryotic replication fork are evolutionarily conserved.

Coordinated replication of eukaryotic genomes is intrinsically asymmetric, with continuous leading strand synthesis preceding discontinuous lagging strand synthesis. Here we provide two types of evidence indicating that, in fission yeast, these two biosynthetic tasks are performed by two different r...

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Bibliographic Details
Main Authors: Izumi Miyabe, Thomas A Kunkel, Antony M Carr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-12-01
Series:PLoS Genetics
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22144917/?tool=EBI