Single-cell transcriptome and cell-specific network analysis reveal the reparative effect of neurotrophin-4 in preantral follicles grown in vitro

Single-cell transcriptome and cell-specific network analysis reveal the reparative effect of neurotrophin-4 in preantral follicles grown in vitro

Abstract Background In-vitro-grow (IVG) of preantral follicles is essential for female fertility preservation, while practical approach for improvement is far from being explored. Studies have indicated that neurotrophin-4 (NT-4) is preferentially expressed in human preantral follicles and may be cr...

Full description

Bibliographic Details
Main Authors: Yingchun Guo, Peigen Chen, Tingting Li, Lei Jia, Yi Zhou, Jiana Huang, Xiaoyan Liang, Chuanchuan Zhou, Cong Fang
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Reproductive Biology and Endocrinology
Subjects:
In-vitro-grow
Preantral follicle
Single-cell transcriptome
NT-4
Fertility preservation
Online Access:https://doi.org/10.1186/s12958-021-00818-w

Internet

https://doi.org/10.1186/s12958-021-00818-w

Similar Items