Coagulation disorders during treatment with cefazolin and rifampicin: rare but dangerous

<p>We describe a 79-year-old man with spondylodiscitis and unknown pathogen, treated with cefazolin and rifampicin. He developed a massive digestive hemorrhage. Prothrombin time was prolonged with severe vitamin-K-dependent clotting-factor deficiency. Severe bleeding can occur during cefazolin...

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Bibliographic Details
Main Authors: I. Kouki, C. Montagner, W. Mauhin, J. London, T. Lazard, S. Grimbert, V. Zeller, O. Lidove
Format: Article
Language:English
Published: Copernicus Publications 2021-04-01
Series:Journal of Bone and Joint Infection
Online Access:https://jbji.copernicus.org/articles/6/131/2021/jbji-6-131-2021.pdf