Extracellular HtrA2 Induces Apoptosis in Human Umbilical Vein Endothelial Cells

Extracellular HtrA2 Induces Apoptosis in Human Umbilical Vein Endothelial Cells

The serine protease high-temperature-required protein A2 (HtrA2) has been identified as a key intracellular molecule promoting apoptosis in cells during ischemia reperfusion (IR) injury. IR injury in ST-segment elevation myocardial infarction (STEMI) contributes to overall myocardial damage. HtrA2 h...

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Bibliographic Details
Main Authors: Gurpinder Kaur, Daniela Stallmann, Nancy Schanze, Rosmarie Laumann, Lukas Andreas Heger, Johannes Steinfurt, Peter Stachon, Karlheinz Peter, Christoph Bode, Martin Moser, Ingo Ahrens, Daniel Duerschmied, Marcus Hortmann
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
htra2 (high temperature required protein a2)
ischemia reperfusion injury
apoptosis
Online Access:https://www.mdpi.com/1422-0067/20/21/5446

Internet

https://www.mdpi.com/1422-0067/20/21/5446

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