Gallbladder carriage generates genetic variation and genome degradation in Salmonella Typhi.

Despite recent advances in typhoid fever control, asymptomatic carriage of Salmonella Typhi in the gallbladder remains poorly understood. Aiming to understand if S. Typhi becomes genetically adapted for long-term colonisation in the gallbladder, we performed whole genome sequencing on a collection o...

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Bibliographic Details
Main Authors: Pham Thanh Duy, Nga Tran Vu Thieu, To Nguyen Thi Nguyen, Ho Ngoc Dan Thanh, Sabina Dongol, Abhilasha Karkey, Megan Carey, Buddha Basnyat, Gordon Dougan, Maia A Rabaa, Stephen Baker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008998