A Novel Circular RNA hsa_circRPPH1_015 Exerts an Oncogenic Role in Breast Cancer by Impairing miRNA-326-Mediated ELK1 Inhibition

A Novel Circular RNA hsa_circRPPH1_015 Exerts an Oncogenic Role in Breast Cancer by Impairing miRNA-326-Mediated ELK1 Inhibition

Background: Breast cancer (BC) represents a heterogeneous disease with distinct subtypes and high tumor metastatic potentials. Recent researchers identify the implication of circular RNAs (circRNAs) in the initiation of BC. Herein, we uncover a novel circRNA hsa_circRPPH1_015 as a tumor promoter in...

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Bibliographic Details
Main Authors: Chunming Zhao, Linlin Li, Zhiwei Li, Jiawen Xu, Qing Yang, Peng Shi, Kaining Zhang, Rui Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Oncology
Subjects:
breast cancer
Circular RNA
hsa_circRPPH1_015
microRNA-326
ELK1
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00906/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.00906/full

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