Expression and Function of RIG-I in Oral Keratinocytes and Fibroblasts

Expression and Function of RIG-I in Oral Keratinocytes and Fibroblasts

Background: Innate immune response by oral mucosal cells may be the first line of host defense against viral infection. Retinoic acid-inducible gene-I (RIG-I) recognizes viral dsRNA in the cytoplasm, and RIG-I-mediated signaling regulates antiviral type I IFN, and inflammatory chemokine production....

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Bibliographic Details
Main Authors: Kouji Ohta, Akiko Fukui, Hideo Shigeishi, Yoko Ishida, Hiromi Nishi, Kei Tobiume, Masaaki Takechi, Nobuyuki Kamata
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
IFN-β
Oral keratinocytes
Oral fibroblasts
RIG-I
CXCL10
Online Access:http://www.karger.com/Article/FullText/366359

Internet

http://www.karger.com/Article/FullText/366359

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