Impact of intrapartum and postnatal antibiotics on the gut microbiome and emergence of antimicrobial resistance in infants

Abstract Altogether, 20–30% of women receive intrapartum antibiotic prophylaxis (IAP) to prevent sepsis in infants and 2–5% of newborn infants receive antibiotics due to suspected sepsis. Caesarean section has a long-term impact on the intestinal microbiome but the effects of perinatal antibiotics o...

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Bibliographic Details
Main Authors: Terhi Tapiainen, Pirjo Koivusaari, Lauren Brinkac, Hernan A. Lorenzi, Jarmo Salo, Marjo Renko, Hannele Pruikkonen, Tytti Pokka, Weizhong Li, Karen Nelson, Anna Maria Pirttilä, Mysore V. Tejesvi
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-46964-5