Mutagenesis facilitated crystallization of GLP-1R

Mutagenesis facilitated crystallization of GLP-1R

The class B family of G-protein-coupled receptors (GPCRs) has long been a paradigm for peptide hormone recognition and signal transduction. One class B GPCR, the glucagon-like peptide-1 receptor (GLP-1R), has been considered as an anti-diabetes drug target and there are several peptidic drugs availa...

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Bibliographic Details
Main Authors: Yueming Xu, Yuxia Wang, Yang Wang, Kaiwen Liu, Yao Peng, Deqiang Yao, Houchao Tao, Haiguang Liu, Gaojie Song
Format: Article
Language:English
Published: International Union of Crystallography 2019-11-01
Series:IUCrJ
Subjects:
mutations
g-protein-coupled receptors
glucagon-like peptide-1 receptor
membrane proteins
molecular dynamic simulations
crystallization
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2052252519013496

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http://scripts.iucr.org/cgi-bin/paper?S2052252519013496

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