A translocated effector required for Bartonella dissemination from derma to blood safeguards migratory host cells from damage by co-translocated effectors.

Numerous bacterial pathogens secrete multiple effectors to modulate host cellular functions. These effectors may interfere with each other to efficiently control the infection process. Bartonellae are Gram-negative, facultative intracellular bacteria using a VirB type IV secretion system to transloc...

Full description

Bibliographic Details
Main Authors: Rusudan Okujava, Patrick Guye, Yun-Yueh Lu, Claudia Mistl, Florine Polus, Muriel Vayssier-Taussat, Cornelia Halin, Antonius G Rolink, Christoph Dehio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4063953?pdf=render