Expression and Transcriptional Regulation of Human ATP6V1A Gene in Gastric Cancers

Abstract Recent studies demonstrate that the invasion and metastasis of gastric cancer (GC) is closely associated with a multi-subunit vacuolar H+-ATPase (V-ATPase). Here we investigated the expression and role of the human ATP6V1A gene that encodes the catalytic subunit A of V-ATPase in GC. We foun...

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Bibliographic Details
Main Authors: Pin Wang, Lei Wang, Jie Sha, Guochun Lou, Nannan Lu, Bo Hang, Jian-Hua Mao, Xiaoping Zou
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03021-3