Small-Molecule-Driven Hepatocyte Differentiation of Human Pluripotent Stem Cells
The differentiation of pluripotent stem cells to hepatocytes is well established, yet current methods suffer from several drawbacks. These include a lack of definition and reproducibility, which in part stems from continued reliance on recombinant growth factors. This has remained a stumbling block...
Main Authors: | Richard Siller, Sebastian Greenhough, Elena Naumovska, Gareth J. Sullivan |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-05-01
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Series: | Stem Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213671115001010 |
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