Impaired Progesterone-Responsiveness of CD11c+ Dendritic Cells Affects the Generation of CD4+ Regulatory T Cells and Is Associated With Intrauterine Growth Restriction in Mice

Impaired Progesterone-Responsiveness of CD11c+ Dendritic Cells Affects the Generation of CD4+ Regulatory T Cells and Is Associated With Intrauterine Growth Restriction in Mice

Up to 10% of pregnancies in Western societies are affected by intrauterine growth restriction (IUGR). IUGR reduces short-term neonatal survival and impairs long-term health of the children. To date, the molecular mechanisms involved in the pathogenesis of IUGR are largely unknown, but the failure to...

Full description

Bibliographic Details
Main Authors: Kristin Thiele, Alexandra Maximiliane Hierweger, Julia Isabel Amambay Riquelme, María Emilia Solano, John P. Lydon, Petra Clara Arck
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Endocrinology
Subjects:
dendritic cells
IUGR
placenta
progesterone
Tregs
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00096/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2019.00096/full

Similar Items