Mitochondria and endoplasmic reticulum crosstalk in amyotrophic lateral sclerosis

Physical and functional interactions between mitochondria and the endoplasmic reticulum (ER) are crucial for cell life. These two organelles are intimately connected and collaborate to essential processes, such as calcium homeostasis and phospholipid biosynthesis. The connections between mitochondri...

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Bibliographic Details
Main Authors: Giovanni Manfredi, Hibiki Kawamata
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996115300267