In silico screening of the key cellular remodeling targets in chronic atrial fibrillation.

Chronic atrial fibrillation (AF) is a complex disease with underlying changes in electrophysiology, calcium signaling and the structure of atrial myocytes. How these individual remodeling targets and their emergent interactions contribute to cell physiology in chronic AF is not well understood. To a...

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Bibliographic Details
Main Authors: Jussi T Koivumäki, Gunnar Seemann, Mary M Maleckar, Pasi Tavi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-05-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4031057?pdf=render