Methylglyoxal-Derived Advanced Glycation Endproducts in Multiple Sclerosis

Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS). The activation of inflammatory cells is crucial for the development of MS and is shown to induce intracellular glycolytic metabolism in pro-inflammatory microglia and macrophages, as well as CNS-resident astrocyt...

Full description

Bibliographic Details
Main Authors: Suzan Wetzels, Kristiaan Wouters, Casper G. Schalkwijk, Tim Vanmierlo, Jerome J. A. Hendriks
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/18/2/421