Cardiac myosin binding protein-C phosphorylation modulates myofilament length-dependent activation

Cardiac myosin binding protein-C phosphorylation modulates myofilament length-dependent activation

Cardiac myosin binding protein-C (cMyBP-C) phosphorylation is an important regulator of contractile function, however, its contributions to length-dependent (SL) changes in cross-bridge (XB) kinetics is unknown. Therefore, we performed mechanical experiments to quantify contractile function in dete...

Full description

Bibliographic Details
Main Authors: Ranganath eMamidi, Kenneth eGresham, Sujeet eVerma, Julian eStelzer
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Physiology
Subjects:
protein kinase A
stretch activation
cross-bridge kinetics
Cardiac myosin binding protein-C
phoshphorylation
skinned myocardium
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00038/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00038/full

Similar Items