Andrographolide Induces Autophagic Cell Death and Inhibits Invasion and Metastasis of Human Osteosarcoma Cells in An Autophagy-Dependent Manner

Andrographolide Induces Autophagic Cell Death and Inhibits Invasion and Metastasis of Human Osteosarcoma Cells in An Autophagy-Dependent Manner

Background/Aims: Osteosarcoma (OS) is the most common primary malignant tumor of bone tissue. Although treatment effectiveness has improved, the OS survival rate has fluctuated in recent years. Andrographolide (AG) has been reported to have antitumor activity against a variety of tumors. Our aim was...

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Bibliographic Details
Main Authors: Ying Liu, Yan Zhang, Jilong Zou, Lixin Yan, Xiufeng Yu, Peng Lu, Xiaomeng Wu, Qiaozhi Li, Rui Gu, Daling Zhu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Andrographolide
Autophagy
Apoptosis
Epithelial-mesenchymal transition
Osteosarcoma
Online Access:https://www.karger.com/Article/FullText/485536

Internet

https://www.karger.com/Article/FullText/485536

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