Cytochrome P450 enzymes: understanding the biochemical hieroglyphs [v1; ref status: indexed, http://f1000r.es/583]

Cytochrome P450 (CYP) enzymes are the primary proteins of drug metabolism and steroid biosynthesis. These crucial proteins have long been known to harbor a cysteine thiolate bound to the heme iron. Recent advances in the field have illuminated the nature of reactive intermediates in the reaction cyc...

Full description

Bibliographic Details
Main Author: John T. Groves
Format: Article
Language:English
Published: F1000 Research Ltd 2015-07-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/4-178/v1