Azathioprine antagonizes aberrantly elevated lipid metabolism and induces apoptosis in glioblastoma

Summary: Glioblastoma multiforme (GBM) is the most aggressive type of brain tumor with poor survival rate. Temozolomide (TMZ) is used as standard chemotherapy to treat GBM, but a large number of patients either respond poorly and/or develop resistance after long-term use, emphasizing the need to dev...

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Bibliographic Details
Main Authors: Hye Jin Nam, Young Eun Kim, Byoung-San Moon, Hyun Young Kim, Daeyoung Jung, Seungho Choi, Jeong Woon Jang, Do-Hyun Nam, Heeyeong Cho
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221002066