Mycobacterial virulence: impact on immunogenicity and vaccine research [version 1; peer review: 4 approved]
The borderline between virulence and efficacy in live attenuated vaccine strains is often blurred and this is also the case for the Bacillus Calmette–Guérin (BCG), the only currently licensed anti-tuberculosis vaccine used on a large, global scale, which was obtained almost 100 years ago. While BCG...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2019-11-01
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Series: | F1000Research |
Online Access: | https://f1000research.com/articles/8-2025/v1 |