Mycobacterial virulence: impact on immunogenicity and vaccine research [version 1; peer review: 4 approved]

The borderline between virulence and efficacy in live attenuated vaccine strains is often blurred and this is also the case for the Bacillus Calmette–Guérin (BCG), the only currently licensed anti-tuberculosis vaccine used on a large, global scale, which was obtained almost 100 years ago. While BCG...

Full description

Bibliographic Details
Main Authors: Vera M. Kroesen, Jan Madacki, Wafa Frigui, Fadel Sayes, Roland Brosch
Format: Article
Language:English
Published: F1000 Research Ltd 2019-11-01
Series:F1000Research
Online Access:https://f1000research.com/articles/8-2025/v1