Activating Telomerase <i>TERT</i> Promoter Mutations and Their Application for the Detection of Bladder Cancer

Activating Telomerase <i>TERT</i> Promoter Mutations and Their Application for the Detection of Bladder Cancer

This review summarizes state-of-the-art knowledge in early-generation and novel urine biomarkers targeting the telomerase pathway for the detection and follow-up of bladder cancer (BC). The limitations of the assays detecting telomerase reactivation are discussed and the potential of transcription-a...

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Bibliographic Details
Main Authors: Maria Zvereva, Eduard Pisarev, Ismail Hosen, Olga Kisil, Simon Matskeplishvili, Elena Kubareva, David Kamalov, Alexander Tivtikyan, Arnaud Manel, Emmanuel Vian, Armais Kamalov, Thorsten Ecke, Florence Le Calvez-Kelm
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
bladder cancer
biomarkers
non-invasive detection
telomerase
somatic mutations
TERT promoter region
Online Access:https://www.mdpi.com/1422-0067/21/17/6034

Internet

https://www.mdpi.com/1422-0067/21/17/6034

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