Tumor necrosis factor receptor-associated protein 1 regulates hypoxia-induced apoptosis through a mitochondria-dependent pathway mediated by cytochrome c oxidase subunit II

Tumor necrosis factor receptor-associated protein 1 regulates hypoxia-induced apoptosis through a mitochondria-dependent pathway mediated by cytochrome c oxidase subunit II

Abstract Background Tumor necrosis factor receptor-associated protein 1 (TRAP1) plays a protective effect in hypoxic cardiomyocytes, but the precise mechanisms are not well clarified. The study is aimed to identify the mechanism of TRAP1 on hypoxic damage in cardiomyocytes. Methods In this study, th...

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Bibliographic Details
Main Authors: Fei Xiang, Si-yuan Ma, Yan-ling Lv, Dong-xia Zhang, Hua-pei Song, Yue-sheng Huang
Format: Article
Language:English
Published: Oxford University Press 2019-05-01
Series:Burns & Trauma
Subjects:
Cardiomyocytes
Hypoxia
Tumor necrosis factor receptor-associated protein 1
Cytochrome c oxidase subunit II
Reactive oxygen species
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s41038-019-0154-3

Internet

http://link.springer.com/article/10.1186/s41038-019-0154-3

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