Reconstruction of the cervical spinal cord based on motor function restoration and mitigation of oxidative stress and inflammation through eNOS/Nrf2 signaling pathway using ibuprofen-loaded nanomicelles

Reconstruction of the cervical spinal cord based on motor function restoration and mitigation of oxidative stress and inflammation through eNOS/Nrf2 signaling pathway using ibuprofen-loaded nanomicelles

Motor disfunction and oxidative and inflammatory stress after spinal cord injuries (SCIs) occur as a result of primary mechanical damage and secondary degeneration process. In the present study, we aimed to examine the protective effect of fabricated ibuprofen- polyethylene glycol (PEG)/polylactide...

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Bibliographic Details
Main Authors: Yang Yang, Lei Zhang, Meiyi Huang, Rubo Sui, Suliman Khan
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Arabian Journal of Chemistry
Subjects:
Spinal cord injury
Cervical
Reconstruction
Nanomicelle
Ibuprofen
Electrophysiology
Online Access:http://www.sciencedirect.com/science/article/pii/S187853522100304X

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http://www.sciencedirect.com/science/article/pii/S187853522100304X

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