Tissue tropisms, infection kinetics, histologic lesions, and antibody response of the MR766 strain of Zika virus in a murine model

Tissue tropisms, infection kinetics, histologic lesions, and antibody response of the MR766 strain of Zika virus in a murine model

Abstract Background The appearance of severe Zika virus (ZIKV) disease in the most recent outbreak has prompted researchers to respond through the development of tools to quickly characterize transmission and pathology. We describe here another such tool, a mouse model of ZIKV infection and pathogen...

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Bibliographic Details
Main Authors: Anna B. Kawiecki, E. Handly Mayton, M. Fausta Dutuze, Brad A. Goupil, Ingeborg M. Langohr, Fabio Del Piero, Rebecca C. Christofferson
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Virology Journal
Subjects:
Zika virus
Mouse model
Neutralizing antibody
Pathogenesis
Histology
Immunohistochemistry
Online Access:http://link.springer.com/article/10.1186/s12985-017-0749-x

Internet

http://link.springer.com/article/10.1186/s12985-017-0749-x

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