Active Turnover of Heme in Hibernation Period in Mammals

Heme oxygenase (HO)-1 plays an important role during hibernation by catalyzing the degradation of heme to biliverdin/bilirubin, ferrous iron, and carbon monoxide, which activates the protective mechanisms against stress. In this context, it was important to analyze the metabolic processes of heme. N...

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Bibliographic Details
Main Authors: Phil Jun Lee, Namki Cho, Hee Min Yoo, Hong Pyo Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01586/full