Coenzyme Q10 suppresses apoptosis of mouse pancreatic β-cell line MIN6

Coenzyme Q10 suppresses apoptosis of mouse pancreatic β-cell line MIN6

Abstract Background In mitochondrial diabetes, apoptosis of β-cells caused by mitochondrial stress plays an important role in impaired insulin secretion. Several studies have reported that coenzyme Q10 (CoQ10) has therapeutic effects on mitochondrial diabetes, but no reports have examined the fundam...

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Bibliographic Details
Main Authors: Keisuke Sumi, Tsuyoshi Okura, Youhei Fujioka, Masahiko Kato, Takeshi Imamura, Shin-ichi Taniguchi, Kazuhiro Yamamoto
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Diabetology & Metabolic Syndrome
Subjects:
MIN6
Coenzyme Q10
Staurosporine
Apoptosis
Mitochondrial diabetes
Online Access:http://link.springer.com/article/10.1186/s13098-018-0351-4

Internet

http://link.springer.com/article/10.1186/s13098-018-0351-4

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