5-HT(2C) receptors localize to dopamine and GABA neurons in the rat mesoaccumbens pathway.

The serotonin 5-HT(2C) receptor (5-HT(2C)R) is localized to the limbic-corticostriatal circuit, which plays an integral role in mediating attention, motivation, cognition, and reward processes. The 5-HT(2C)R is linked to modulation of mesoaccumbens dopamine neurotransmission via an activation of γ-a...

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Bibliographic Details
Main Authors: Marcy J Bubar, Sonja J Stutz, Kathryn A Cunningham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3110193?pdf=render